🧪 Lacture - 4 Drug Metabolism (Biotransformation): Phase I & Phase II — The Easiest Explanation Ever!
Drug Metabolism is one of those topics that looks tough… until someone explains it simply. So today, let’s break it down in the most understandable and exam-friendly way! Whether you're preparing notes, revising for viva, or writing answers in exams — this post is all you need. 🙌 🌟 What is Drug Metabolism? Drug Metabolism (Biotransformation) means: 👉 The chemical modification of drugs inside the body to make them easier to excrete. The body mainly metabolizes drugs in the liver (but lungs, kidney, intestine & skin also help). Main goal of metabolism: ✔ Convert lipid-soluble drugs → into water-soluble forms ✔ So they can be easily eliminated via urine or bile 🧿 Why Do We Need Drug Metabolism? Because most drugs are fat-soluble. Without metabolism, they would stay in the body for days or months! Metabolism helps in: Detoxification Drug inactivation Drug activation (Prodrugs → Active drugs) Preventing drug accumulation 🔥 The Two Phases of Drug Metab...