Drug of the Day: Losartan(Drug of the Day Series – PharmaEasyNotes)
Hypertension (high blood pressure) is one of the most common lifestyle diseases today. And one drug that plays a key role in controlling it is Losartan. 👉 Let’s understand this drug in a simple, exam-oriented and practical way. 🔍 Basic Information Drug Name: Losartan Drug Class: Angiotensin II Receptor Blocker (ARB) Category: Antihypertensive drug 📌 Losartan was the first ARB approved for clinical use. 🧠 Mechanism of Action (Easy Language) Losartan works by: ✔ Blocking Angiotensin II receptors (AT₁) ✔ Preventing vasoconstriction ✔ Reducing aldosterone secretion ✔ Lowering blood pressure smoothly 👉 Result: Blood pressure decreases without severe cough 📌 Important point: Unlike ACE inhibitors, ARBs do not cause dry cough. 🫀 Therapeutic Uses Losartan is used in: Hypertension Diabetic nephropathy Heart failure Stroke risk reduction ✔ Very common in diabetic + hypertensive patients 💊 Dosage (General) 25–100 mg once daily (oral) Dose adjusted based on patient condition ⚠️ Always pres...