Doxycycline – Uses, Mechanism, Dose, Side Effects & Counseling (Drug of the Day)
๐ Doxycycline – Uses, Mechanism, Dose, Side Effects & Counseling (Drug of the Day) Generic Name: Doxycycline Drug Class: Tetracycline Antibiotic Category: Broad-spectrum bacteriostatic antibiotic ๐ Introduction Doxycycline is a widely prescribed tetracycline antibiotic used to treat respiratory infections, acne, STDs, and zoonotic infections. It works against both Gram-positive and Gram-negative bacteria and is also effective against atypical organisms. ๐ In exams, doxycycline is frequently asked because of its unique mechanism and contraindication in children & pregnancy. ⚙️ Mechanism of Action Doxycycline inhibits bacterial protein synthesis. Binds to 30S ribosomal subunit Blocks attachment of aminoacyl-tRNA Prevents addition of amino acids to peptide chain Stops bacterial growth (bacteriostatic) ๐ Key Point: Tetracyclines inhibit protein synthesis but do not kill bacteria directly. ๐ฆ Spectrum of Activity Effective Against: Chlamydia Mycoplasma Rickettsia Bor...