🧠 Pharmacology MCQs Practice – Complete Blog Post (With Explanations)

Want to score high in Pharmacology without memorizing 500 pages?

Here’s the truth: Top students don’t just read Pharmacology — they practice MCQs daily.

MCQs train your brain to:

recall faster 🧠

understand mechanisms

avoid silly mistakes in exams

revise entire syllabus in minutes

So below is a high-yield Pharmacology MCQ practice set — exam-oriented + concept-based.

🧪 General Pharmacology MCQs

1. Bioavailability of an IV administered drug is:

A. 25%

B. 50%

C. 75%

D. 100%

Answer: D. 100%

Concept: IV drugs directly enter systemic circulation → no first pass metabolism.

2. First pass metabolism mainly occurs in:

A. Kidney

B. Liver

C. Lung

D. Plasma

Answer: B. Liver

Concept: Oral drugs go through portal circulation → metabolized before reaching blood.

3. Competitive antagonist shifts dose-response curve to:

A. Left

B. Right

C. Upward

D. Downward

Answer: B. Right

Concept: Higher dose needed → potency decreases but efficacy same.

4. Therapeutic Index represents:

A. Potency

B. Safety

C. Toxicity

D. Efficacy

Answer: B. Safety

Formula: TI = TD50 / ED50

🧠 ANS Pharmacology MCQs

5. Atropine blocks which receptor?

A. Alpha

B. Beta

C. Muscarinic

D. Nicotinic

Answer: C. Muscarinic

Important: Antidote in organophosphate poisoning.

6. Propranolol is:

A. Selective β1 blocker

B. Non-selective β blocker

C. Alpha blocker

D. Calcium channel blocker

Answer: B. Non-selective β blocker

7. Salbutamol is used for:

A. Hypertension

B. Asthma

C. Ulcer

D. Epilepsy

Answer: B. Asthma

Mechanism: β2 agonist → bronchodilation

8. Adrenaline causes:

A. Bronchoconstriction

B. Bradycardia

C. Bronchodilation

D. Hypotension

Answer: C. Bronchodilation

❤️ Cardiovascular Pharmacology MCQs

9. Nitroglycerin is used in:

A. Angina

B. Asthma

C. Epilepsy

D. Diabetes

Answer: A. Angina

Concept: Venodilation ↓ preload ↓ cardiac workload

10. ACE inhibitors act by:

A. Blocking calcium channels

B. Blocking Angiotensin II formation

C. Increasing sodium

D. Increasing heart rate

Answer: B. Blocking Angiotensin II formation

11. Furosemide belongs to:

A. Thiazide diuretic

B. Loop diuretic

C. Osmotic diuretic

D. Potassium-sparing

Answer: B. Loop diuretic

🧬 CNS Pharmacology MCQs

12. Diazepam is a:

A. Barbiturate

B. Benzodiazepine

C. Antipsychotic

D. Antidepressant

Answer: B. Benzodiazepine

13. Phenytoin is used in:

A. Parkinson’s disease

B. Epilepsy

C. Depression

D. Migraine

Answer: B. Epilepsy

14. Haloperidol is:

A. Sedative

B. Antipsychotic

C. Analgesic

D. Hypnotic

Answer: B. Antipsychotic

🦠 Chemotherapy / Antibiotics MCQs

15. Penicillin inhibits:

A. Protein synthesis

B. Cell wall synthesis

C. DNA synthesis

D. RNA synthesis

Answer: B. Cell wall synthesis

16. Tetracycline is contraindicated in:

A. Elderly

B. Children & pregnancy

C. Hypertension

D. Fever

Answer: B. Children & pregnancy

Reason: Teeth discoloration

17. Metronidazole is drug of choice for:

A. Tuberculosis

B. Amoebiasis

C. Malaria

D. Typhoid

Answer: B. Amoebiasis

18. Gentamicin major toxicity:

A. Hepatotoxicity

B. Nephrotoxicity & Ototoxicity

C. Cardiotoxicity

D. Neurotoxicity

Answer: B. Nephrotoxicity & Ototoxicity

🩸 Endocrine Pharmacology MCQs

19. Insulin decreases:

A. Blood glucose

B. Blood pressure

C. Heart rate

D. Temperature

Answer: A. Blood glucose

20. Levothyroxine treats:

A. Hyperthyroidism

B. Hypothyroidism

C. Diabetes

D. Cushing syndrome

Answer: B. Hypothyroidism

🚀 How to Use MCQs to Master Pharmacology

Daily routine for toppers:

Read topic (20 min)

Solve 10 MCQs (10 min)

Revise wrong answers (5 min)

Repeat after 48 hours

👉 This boosts retention up to 80%

Final Tip

Pharmacology is not about memory — it is about pattern recognition.

Practice daily and you’ll start predicting answers before reading options.