Limit Test for Sulphates (IP)Easy Notes for Pharmacy Students | PharmaEasyNotes

📌 Introduction

Limit test for sulphates ek important pharmaceutical analysis test hai jo ye ensure karta hai ki drug substance me sulphate impurities prescribed limit se zyada na ho.

Ye test B.Pharm, D.Pharm aur Pharm.D exams me frequently poocha jata hai.

👉 Ye blog Limit Test Series ka next part hai, jo PharmaEasyNotes par students ke liye specially design kiya gaya hai.

🎯 Objective of Limit Test for Sulphates

Drug substance me sulphate impurity detect karna

Ye confirm karna ki sulphate pharmacopoeial limit ke andar hai

🧪 Principle

Sulphate ions, barium chloride reagent ke sath react karke barium sulphate (BaSO₄) ka white turbidity banate hain.

📌 Reaction:

SO₄²⁻ + BaCl₂ → BaSO₄ (White turbidity)

👁️ Test solution ki turbidity ko standard sulphate solution se compare kiya jata hai.

🧴 Reagents Required

Barium chloride reagent

Dilute hydrochloric acid

Distilled water

Standard sulphate solution

👉 Exam tip: Reagents ke naam short answer me bhi pooche ja sakte hain.

🔬 Procedure

🔹 Test Solution

Given substance ko distilled water me dissolve karein

Dilute HCl add karein

Barium chloride reagent add karein

Achhi tarah mix karke 5 minutes tak stand karne dein

🔹 Standard Solution

Standard sulphate solution lein

Same reagents aur same conditions follow karein

📊 Observation

Test solution me jo turbidity develop hoti hai

Uska comparison standard solution se kiya jata hai

✅ Acceptance Criteria

✔ Test solution ki turbidity

👉 Standard solution se zyada nahi honi chahiye

Agar zyada ho → ❌ Substance fail

Agar kam ya equal ho → ✅ Substance pass

⚠️ Precautions

Glassware bilkul clean ho

Same time interval follow karein

Proper lighting me turbidity observe karein

Reagents fresh hone chahiye

👉 Ye points viva me directly pooche ja sakte hain.

📝 Viva Voce Questions (Important)

Q1. Limit test ka main purpose kya hai?

👉 Impurities ko prescribed limit me rakhna

Q2. Sulphate test me kaunsa precipitate banta hai?

👉 Barium sulphate

Q3. Turbidity comparison kyun kiya jata hai?

👉 Accurate impurity estimation ke liye

⭐ Exam Importance

📌 5 marks long question

📌 Short notes

📌 Practical viva

📌 MCQs

👉 Isliye ye topic exam + practical dono ke liye must-read hai.

📥 Free Resource (Blog Growth Trick)

🎁 Free PDF: Limit Test for Sulphates – One Page Revision Sheet

👉 Download only on PharmaEasyNotes

(Ye CTA aapke blog par conversion badhata hai)

🔗 Internal Linking (SEO Boost)

Limit Test for Chlorides

Limit Test for Iron

Pharmaceutical Analysis Notes PDF