Pharma Easy Notes @Pharmacy

📌 Introduction Antihistaminic drugs are medicines that block the action of histamine, a chemical released during allergic reactions. Histamine causes: 👉 Sneezing, itching, redness 👉 Swelling, watery eyes 👉 Increased gastric acid secretion To control these effects, antihistamines are used in allergy and acid-related disorders. 🧬 What is Histamine? Histamine is a biogenic amine stored in mast cells and basophils. It acts on receptors: H1 → Allergy symptoms H2 → Acid secretion H3, H4 → CNS & immune system (less common in syllabus) 👉 In medicinal chemistry, mainly H1 & H2 blockers are studied. 📊 Classification of Antihistaminic Drugs (Flowchart) Antihistaminic Drugs                          |           --------------------------------           |                              | ...

💊 Drug of the Day: Pantoprazole Category: Proton Pump Inhibitor (PPI) Used For: Acidity, GERD, Ulcers, Acid Reflux Route: Oral / Injection Prescription Status: Prescription Medicine 📌 Introduction Pantoprazole is a widely used anti-ulcer and anti-acidity medicine. It works by reducing excess acid production in the stomach, helping in the treatment of acid-related disorders. It is commonly prescribed in patients suffering from heartburn, gastric ulcers, and gastroesophageal reflux disease (GERD). ⚙️ Mechanism of Action Pantoprazole belongs to the Proton Pump Inhibitor (PPI) class. 👉 It works by: Blocking the H⁺/K⁺ ATPase enzyme in stomach cells Reducing gastric acid secretion Maintaining stomach pH ✔️ Result: Less acid → Less irritation → Faster healing 🩺 Indications (Uses) Pantoprazole is used in: ✅ GERD (Acid Reflux) ✅ Peptic Ulcer Disease ✅ Zollinger-Ellison Syndrome ✅ Erosive Esophagitis ✅ NSAID-induced ulcers ✅ Hyperacidity 💊 Dosage & Administration 👉 Usual Ad...