Part - 2 IPC MCQ 11-25 Radio Pharmaceutical || PharmaEasyNotes || @Pharm...

  • 11. 
    Why are radioisotopes Tc99m-labeled ECD and hexamethylpropylene HMPAO preferred for evaluation of brain death?
    • A. 

      They have a short half-life

    • B. 

      They are brain specific agents which allows for delayed imaging

    • C. 

      They have few side effects which allows for delayed imaging

    • D. 

      They have a long half-life which allows for delayed imaging


      ANS. B 

  • 12. 
    What characteristic of F-18 FDG makes it useful in tumor imaging?
    • A. 

      The glucose component

    • B. 

      The fluorine component

    • C. 

      The phosphate component

    • D. 

      The short half-life


      ANS. A

  • 13. 
    Why does the above characteristic make F-18 FDG useful in tumor imaging? 
    • A. 

      Tumors are hypometabolic and require less fluorine than most normal tissues

    • B. 

      Tumors are hypometabolic and require less sugar than most normal tissues

    • C. 

      Tumors are hypermetabolic and require more fluorine than most normal tissues

    • D. 

      Tumors are hypermetabolic and require more sugar than most normal tissues


      ANS. D

  • 14. 
    How are radioisotopes employed for infection detection? 
    • A. 

      By tagging red blood cells with radioactivity

    • B. 

      By tagging somatostatin receptors with radioactivity

    • C. 

      By tagging white blood cells with radioactivity

    • D. 

      By inhaling radioactive gas


      ANS. C 

  • 15. 
    Why is F-18 fluorodeoxyglucose useful in imaging neuronal activity in the brain? 
    • A. 

      Because the brain uses fluorine for energy

    • B. 

      Because the brain uses glucose for energy

    • C. 

      Because diseased brain tissue requires an excess of glucose

    • D. 

      Because diseased brain tissue requires an excess of fluorine


      ANS. B 

  • 16. 
    Gastrointestinal bleeding can be detected using nuclear medicine imaging regardless of whether or not the patient is actively bleeding at the time of radiotracer injection.
    • A. 

      True

    • B. 

      False


      ANS. B  

  • 17. 
    When is quantification of lung function useful? 
    • A. 

      To evaluate for pulmonary embolism

    • B. 

      To evaluate for COPD

    • C. 

      To assess lung function pre or post-surgery

    • D. 

      All of the above


      ANS. C

  • 18. 
    What is often administered to patients during imaging of bladder-emptying in renal scintigraphy?
    • A. 

      A sedative

    • B. 

      A diuretic

    • C. 

      IV saline

    • D. 

      An anesthetic


      ANS. B 

  • 19. 
    A region of interest is drawn around what organ to assess biliary function? 
    • A. 

      Liver

    • B. 

      Stomach

    • C. 

      Intestine

    • D. 

      Gallbladder


      ANS. D 

  • 20. 
    Why is sulfur colloid preferred in gastric emptying studies? 
    • A. 

      It’s easy to digest

    • B. 

      It’s tasteless

    • C. 

      It is not absorbed by surrounding tissues

    • D. 

      It’s easily absorbed by surrounding tissues


      ANS. C

  • 21. 
    What is the route of administration for a lymphoscintigraphy study?
    • A. 

      Subcutaneously

    • B. 

      Intravenously

    • C. 

      Orally

    • D. 

      None of the above


      ANS. A

  • 22. 
    How do therapeutic radioisotopes generally compare to diagnostic radioisotopes? 
    • A. 

      They have a longer half-life

    • B. 

      They have a higher energy

    • C. 

      They have a shorter half-life

    • D. 

      A & b

    • E. 

      B & c


      ANS. D

  • 23. 
    What kind of radioactivity is emitted by I-131?
    • A. 

      Gamma

    • B. 

      Beta

    • C. 

      Positron

    • D. 

      A & b

    • E. 

      B & c


      ANS. D

  • 24. 
    What is the most commonly used palliative treatment for bone metastasis in the United States?
    • A. 

      P-32

    • B. 

      Sr-89

    • C. 

      Sm-153

    • D. 

      I-131


      ANS. C 

  • 25. 
    What do the pharmaceuticals I-131 tositumomab and Y-90 ibritumomab have in common?
    • A. 

      They can both be imaged for evaluation of biodistribution

    • B. 

      They both target the CD20 antigen on B-lymphocytes

    • C. 

      They both are used to treat Non-Hodgkin’s Lymphoma

    • D. 

      A & b

    • E. 

      B & c


      ANS. E




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