Drug of the Day: Metformin(Most prescribed antidiabetic drug | Exam + Industry important)
Metformin is one of the most commonly used oral antidiabetic drugs worldwide. Because of its high clinical use, frequent exam questions, and industry relevance, it is a perfect drug for the Drug of the Day series on PharmaEasyNotes. ๐ฌ Generic Name Metformin ๐ท️ Brand Names Glyciphage, Gluformin, Glycomet, Obimet ๐งช Drug Class Biguanide Antidiabetic Agent ๐ง Mechanism of Action (Easy to Remember) Metformin works mainly by: ✔ Decreasing hepatic glucose production ✔ Increasing insulin sensitivity ✔ Reducing intestinal absorption of glucose ๐ Important: ๐ Metformin does NOT cause hypoglycemia when used alone. ๐ Therapeutic Uses Type 2 Diabetes Mellitus Polycystic Ovary Syndrome (PCOS) Insulin resistance Prevention of diabetes in high-risk patients ⚠️ Side Effects Common: Nausea Diarrhea Abdominal discomfort Rare but serious: Lactic acidosis (very important for exams ⚠️) ❌ Contraindications Severe renal impairment Severe liver disease Alcoholism Conditions causing hypoxia ๐ฆ Dosage Form...