💊 Drug of the Day: LosartanCategory: AntihypertensiveDrug Class: ARB (Angiotensin II Receptor Blocker)
Introduction Losartan is a widely used drug for the treatment of high blood pressure (hypertension). It helps protect the heart, kidneys, and blood vessels, making it very important in both clinical practice and exams. ⚙️ Mechanism of Action (Easy to Remember) Blocks Angiotensin II receptors (AT₁) Prevents vasoconstriction Reduces aldosterone release Result 👉 Blood pressure decreases 📌 Mnemonic: “LOSAR-tan = Lose AR (Angiotensin Receptor)” 🧪 Uses of Losartan ✔ Hypertension ✔ Diabetic nephropathy ✔ Heart failure (adjunct therapy) ✔ Stroke risk reduction 💊 Dose (General) Adults: 25–100 mg/day (once or twice daily) (Dose may vary depending on patient condition) ⚠️ Side Effects Dizziness Hypotension Hyperkalemia Headache ❌ Contraindications Pregnancy 🚫 Severe renal artery stenosis 📚 Exam-Oriented Points Belongs to ARB class Does not cause cough (unlike ACE inhibitors) Safer alternative to ACE inhibitors Common comparison question: 👉 Losartan vs Enalapril 🧠 Quick MCQs (For Stud...