💊 Drug of the Day: LosartanCategory: AntihypertensiveDrug Class: ARB (Angiotensin II Receptor Blocker)

 Introduction

Losartan is a widely used drug for the treatment of high blood pressure (hypertension). It helps protect the heart, kidneys, and blood vessels, making it very important in both clinical practice and exams.

⚙️ Mechanism of Action (Easy to Remember)

Blocks Angiotensin II receptors (AT₁)

Prevents vasoconstriction

Reduces aldosterone release

Result 👉 Blood pressure decreases

📌 Mnemonic:

“LOSAR-tan = Lose AR (Angiotensin Receptor)”

🧪 Uses of Losartan

✔ Hypertension

✔ Diabetic nephropathy

✔ Heart failure (adjunct therapy)

✔ Stroke risk reduction

💊 Dose (General)

Adults: 25–100 mg/day (once or twice daily)

(Dose may vary depending on patient condition)

⚠️ Side Effects

Dizziness

Hypotension

Hyperkalemia

Headache

❌ Contraindications

Pregnancy 🚫

Severe renal artery stenosis

📚 Exam-Oriented Points

Belongs to ARB class

Does not cause cough (unlike ACE inhibitors)

Safer alternative to ACE inhibitors

Common comparison question:

👉 Losartan vs Enalapril

🧠 Quick MCQs (For Students)

Q1. Losartan belongs to which drug class?

A. ACE inhibitor

B. Beta blocker

C. ARB ✅

D. Diuretic

Q2. Major advantage of Losartan over ACE inhibitors?

A. Less cost

B. No cough ✅

C. Faster action

D. Sedation

💬 Student Engagement Box

📢 Question for you:

Which ARB drug do you find most confusing?

🔘 Losartan

🔘 Telmisartan

🔘 Valsartan

🔘 Olmesartan

Comment below 👇

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